Our research transcends the full spectrum of "populations health" but in considering the health burdens unique to the northeast Ohio region, as well as the strengths and priorities of the Cleveland Clinic enterprise, CPHR maintains a focus on the following broad areas:
Access to affordable healthcare was selected as one of the most significant health needs in the communities served by Cleveland Clinic main campus, as well as the northeast Ohio region in the Statewide Health Assessment. Access to basic medical care was identified by nearly all interviewees as problematic, and many rely excessively on emergency departments for primary care needs. Lack of transportation options is a significant barrier to good health, especially affecting those with low-income, the elderly, and those with disabilities. Specific issues important to our community include the following:
Between 2012 -2015, infant mortality in Cleveland was double the national average. Upon examination of neighborhoods, pre-term infants born in the Lee-Harvard neighborhood die nearly 8 times the rate as pre-term infants born in the Buckeye-Woodhill neighborhood, just 4 miles away. More than half of the counties in Cleveland Clinic's 21 county-community had unfavorable rates of infant and neonatal mortality. Contributing factors include poverty, poor housing, smoking rates, lack of time between pregnancies, weigh management issues, and lack of access to and knowledge of prenatal services. Community collaboration is essential.
36% of residents in Cuyahoga county live in a food desert, and diabetes and obesity were ranked 2nd in the 2016 Community Health Needs Assessment conducted by the organization, for both Cleveland Clinic children's hospital and Cleveland Clinic Main Campus.
In 2017, Cuyahoga County saw an average of more than 45 deaths per month attributed to opioids. Already by September 2018, the total number of fatalities attributable to opioid overdoses has surpassed the total in 2017.
Quality assurance and improvement is a critical part of any health system. As measurements and methods become more accurate, many organizations are striving to understand how best to incorporate social determinants of health indicators (SDOH) to give a more holistic picture of the quality being provided. The National Quality Forum has put together a multidisciplinary team of experts to advise on integrating these SDOH indicators into clinical practice in a way that is actionable and aims to improve healthcare access and outcomes. Within the Cleveland Clinic, we will also be examining interventions and processes focused on improving quality, and working across disciplines to make efforts more inclusive of data that is collected outside the walls of a health clinic.
Methodology for populations health research is a dynamic area with new insights continuing to emerge. In the past, population-level interventions and policies have been implemented in a blanketed fashion, with recommendations targeted at an entire community, patient population, or disease group. However, new research is showing that risk profiles and models are not evenly applied across various types of populations, and so, recommendations should be appropriately tailored to take that into account. Incorporating risk heterogeneity, intersectionality, and public engagement approaches into populations health research can help to ensure findings are accurate regardless of race, age, or gender, and begin to address issues of health equity.
| Award Period | Investigator (s) | Affiliation | Project Title | Dataset |
|---|---|---|---|---|
| Q2 2022 | Diya Ramanathan; Brandon Hopkins | Pediatrics | Association of Discharge Location Following Pediatric Tracheostomy with Social Determinants of Health: A National Cohort Analysis | KID |
| Q2 2022 | Tushar Vachharajani; Tarik Hanane; James Lane; Cheodize Udeh | Intensive Care Unit | Cost-Effective Strategy to Achieve Central Venous Access in the Critically Ill Population | CC MICU Registry |
| Q2 2022 | Maeve Hopkins, MD and Margaret Kuder, MD | Obstetrics | Clinical and Economic Impact of Penicillin Allergy Testing in Obstetric Patients | Literature & IBM Micromedex Redbook database |
| Q2 2022 | Akhil Anand; Shreya Sengupata; Jeremy Weleff | Neurological | Ambulatory Utilization by Patients with Alcoholic Hepatitis: Results of National Survey | NEDS |
| Q1 2022 | Carli Lehr; Maryam Valapour | Respiratory | Economic Trends in End of Life Hospitalization for Individuals with Pulmonary Disease | National Inpatient Sample |
| Q1 2022 | Corey Gentle | Bariatric & Metabolic | Food Insecurity in Bariatric Surgery: Exploring the Impact of Geospatial Disparities on Surgical and Nutritional Outcomes after Roux-en-Y Gastric Bypass and Sleeve Gastrectomy | MBSAQIP (CCF) |
| Q1 2022 | Matthew Siuba | Respiratory | Allocation of veno-venous extracorporeal membrane oxygenation in acute respiratory distress syndrome before and during the COVID-19 pandemic: assessment of hospital outcomes and health disparities | SID |
| Q1 2022 | Shahnawaz Amdani | Pediatric | Trends in 30 and 60 Day Readmission Rates for Children with Heart Failure | NRD |
| Q3 2021 | Shahnawaz Amdani | Pediatric | 5-tier assessment of heart transplant programs leads to 5-tiers of confusion | SRTR |
| Q3 2021 | Deborah Miller; Justin Abbatemarco | Mellen Center | Unique Contribution of Race to Disability in Multiple Sclerosis | Mellen Center Registry |
| Q3 2021 | Brian Barnett | Neurological | Interrogating the relationship between LSD use, availability, and associated risk perceptions at the population level | NSDUH |
| Q2 2021 | Saket Saxena | Medicine | Predictive model to identify High Risk Geriatric Patients in Emergency Department | HER and billing |
| Q2 2021 | Michelle Beidelschies | Community Health | Association of Environmental Exposures/Toxicants With Self-Reported Rheumatoid Arthritis: An NHANES Study (2007-2016) | NHANES |
| Q1 2021 | Shumei Man | Neurological | Disparity of Home Discharge after Stroke Hospitalization | NIS |
| Q1 2021 | Reena Mehra | Neurological | Elucidating Sleep-Related Health Disparities across Morbidity and Prediction of Cardiovascular Events and Mortality Leveraging a Large-Scale Sleep Registry | Sleep Registry, SDOH; ODH |
| Q1 2021 | Amy Attaway | Respiratory | COPD-related sarcopenia is a major public health issue that increases the risk for poor clinical outcomes and mortality | UK BioBank |
| Q2 2020 | Carli Lehr | Pulmonary Medicine | The Impact of New Extracorporeal Membrane Oxygenation Variables on Disease-Specific Transplant Outcomes | SRTR |
| Q2 2020 | Wayne Tsuang | Respiratory | Improving lung transplant outcomes through understanding organ donor social determinants of health | SRTR & County Health Rankings |
| Q2 2020 | Deborah Miller | Neurology | Social Determinants of Health in Patients with Multiple Sclerosis | Mellen registry + public data for SDOH |
| Q1 2020 | Miriam AlHilli | Women's Health | Preoperative Frailty Assessment to Predict Postoperative Outcomes in Patients Undergoing Gynecologic Surgery | NSQIP |
| Q1 2020 | Lisa Hickman; Katie Propst | Women's Health | Defining the epidemiology of obstetric anal sphincter injuries in the United States | NIS |
| Q1 2020 | Shahnawaz Amdani | Peds Cardiology | National burden of pediatric heart failure in the United States | NEDS, NIS, KID, NVSS |
| Q1 2020 | Srinivas Mummadi | Respiratory | The Intersection of Asthma and Metabolic Syndrome: Insights from the United States Population | NHANES |
| Q3 2019 | Shahnawaz Amdani | Children's Hospital | The Association of Center Performance Evaluations to Candidate Removals from the Waitlist and Pediatric Heart Transplant Volumes in the United States | SRTR |
| Q3 2019 | Matthew Siuba | Respiratory | 30-day Readmission in Adults with Acute Respiratory Distress Syndrome: Risk Factors and Epidemiology | NRD 2016 |
| Q3 2019 | Neha Solanki | Respiratory | Asthma exacerbations in Cleveland OH vs. Sacramento, CA and how they correlate to Air Quality Index | SID, AQS Datamart |
| Q3 2019 | Srinivas Mummadi | Respiratory | Epidemiology of Pleural Disease (adults) in the United States (2006-2015) | NIS, NEDS, NRD |
| Q2 2019 | Peng Zhang | Respiratory | Social and economic determinants of diet composition and their effect on asthma | NHANES |
| Q2 2019 | Jeremy Weleff | Psychiatry | Characterization of homeless patients admitted to inpatient psychiatry and the role of homelessness on healthcare service utilization and readmission | Epic |
| Q2 2019 | Susannah Rose | Patient Experience | Predicting Patient Experience: Assessing the Factors Associated with Improving Patient Experience | CAHPS |
| Q2 2019 | Karen Distelhorst | Nursing | Health Care Utilization and Neighborhood Disadvantage in Vulnerable Patients with Food Insecurity | Epic |
| Q1 2019 | Mladen Golubic | Wellness | Amelioration of Chronic Pain and Opioid Crisis via the Non-pharmacologic "Living Well With Chronic Pain" Shared Medical Appointments | PROMIS |
| Q1 2019 | Ruth Farrell | Women's Health | Examining the role of telehealth in increasing access and decreasing costs for contraceptive services | MEPS; VirtV/Epic |
| Q1 2019 | Maeve MacMurdo | Respiratory | Indirect morbidity, mortality and cost from substance use in patients with chronic lung disease. | NRD, NEDS |
| Q1 2019 | Shumei Man | Neurologic | The Disparities of Readmission after Ischemic Stroke Hospitalization (DRISH-Study) | SID |
| Q4 2018 | Ken Uchino; Dinesh Jillella | Neurologic | Cerebrovascular Risk Factors in Native Americans with Ischemic Stroke | NIS |
| Q4 2018 | Benjamin Click | Digestive Disease & Surgery | Changing Cost-Drivers of Healthcare Spending for Inflammatory Bowel Disease over Two Decades | MEPS |
| Q4 2018 | Emi Bretschneider | Women's Health | Analysis of rates, trends, and cost associated with readmission following hysterectomy | SID, SASD |
| Q4 2018 | Amandeep Singh | Digestive Disease & Surgery | Dietary habits and natural history of NAFLD in US population | NHANES |
| Q3 2018 | Joseph Zein | Respiratory | Risk factors for recurrent asthma hospital visits and death | Epic |
| Q3 2018 | Roy Kim | Internal Medicine/Pediatrics | Adherence to a Mediterranean diet and the metabolic syndrome in U.S. adolescents | NHANES |
| Q3 2018 | Carli Lehr | Respiratory | The impact of increased risk donors on survival after lung transplantation | |
| Q3 2018 | Wayne Tsuang | Respiratory | Patient Travel Distance and Access to Lung Transplant Care: A National Cohort Study | SRTR |
| Q3 2018 | Tae Hyun Hwang | Quantitative Health Sciences | Computational Analysis of Opioid Poisoning Mortality in Ohio from 2010-2016 | ODH |
| Q3 2018 | Shumei Man; Ken Uchino | Neurologic | Patterns and Outcomes of Interhospital Transfer for Acute Ischemic Stroke | MEDPAR |
Amdani S, Gossett JG, Chepp V, Urschel S, Asante-Korang A and Dalton JE. Review on clinician bias and its impact on racial and socioeconomic disparities in pediatric heart transplantation. Pediatric Transplantation (in press)
Barnett, B. S., Anand, A., Dewey, E. N., Smith, D., Nayak, S. M., Bruckman, D., & Weleff, J. (2024). Perceived Risk of Trying Lysergic Acid Diethylamide in the United States from 2015 to 2019: Are Americans Assessing Lysergic Acid Diethylamide's Risk Profile More Favorably? Psychedelic Medicine.
Bilen Y, Schold JD, Arrigain S, Buchalter RB, Huml AM. Relationship of Social Deprivation Among Living Kidney Donor–Recipient Pairs. Transplantation Direct. 2024;10(1):e1559. doi:10.1097/TXD.0000000000001559
Blazel MM, Perzynski AT, Gunsalus P, Mourany L, Gunzler D, Jones R, Pfoh ER, Dalton J. Neighborhood-level disparities in hypertension prevalence and treatment among mid-life adults. JAMA Network Open. In press.
Boakye KA, Iyanda AE, Buchalter RB. A spatial approach to uncovering the socio-environmental injustice of noise pollution. Local Environ. In press
Buchalter RB, Mohan S, Schold JD. Geospatial modeling methods in epidemiological kidney research: An overview and practical example. Kidney International Reports (in press)
Buchalter RB, Mohan S, Schold JD. Geospatial modeling methods in epidemiological kidney research: An overview and practical example. Kidney International Reports. 2024;0(0). doi:10.1016/j.ekir.2024.01.017
Buchalter RB, Stern MC, Mendez JS, Kim MK, Rose J, Meade CD, Gwede CK, Figueiredo JC, Schmit SL. Identification of priority areas for colorectal cancer screening interventions among U.S. Hispanic/Latino populations. Am J Public Health. 2024. In press.
Duggal A, Scheraga R, Sacha GL, Wang X, Huang S, Krishnan S, Siuba M, Torbic H, Dugar S, Mucha S, Veith J, Mireles-Cabodevila E, Bauer SR, Kethireddy S, Vachharajani V, and Dalton J. Forecasting disease trajectories in critical illness: comparison of probabilistic dynamic systems to static models to predict patient status in the intensive care unit. BMJ Open (accepted)
Gunsalus PR, Rose J, Lehr CJ, Valapour M*, and Dalton JE*. Creating synthetic populations in transplantation: a Bayesian approach enabling simulation without registry re-sampling. PLoS One (accepted)
Ho VP, Towe CW, Bensken WP, Pfoh E, Dalton J, Conners A, Claridge JA and Perzynski A. The mortality burden from variation in provision of surgical care in emergency general surgery. Trauma Surgery & Acute Care Open Jun 25;9(1):e001288. doi: 10.1136/tsaco-2023-001288. 2024
Johnie Rose, Paul R. Gunsalus, Carli J. Lehr, Mark F. Swiler, Jarrod E. Dalton, Maryam Valapour. A Modular Simulation Framework for Organ Allocation, The Journal of Heart and Lung Transplantation, 2024; In Press
Lehr CJ, Dewey E, Udeh B, Dalton JE, and Valapour M. Costs of end-of-life hospitalizations for individuals with pulmonary diseases in the United States. CHEST (in press)
Lehr, C. J., Dalton, J. E., Dewey, E. N., Gunsalus, P. R., Rose, J., & Valapour, M. (2024). Differential Effects of donor Factors on Post-Transplant survival in lung transplantation. JHLT Open, 100122.
Man S, Bruckman D, Uchino K, Schold JD, Dalton J. Racial, Ethnic, and Regional Disparities of Post-Acute Service Utilization After Stroke in the United States. Neurol Clin Pract. 2024 Oct;14(5):e200329. doi: 10.1212/CPJ.0000000000200329. Epub 2024 Jul 17. PMID: 39036785; PMCID: PMC11259533.
McGinley MP, Harvey T, Lopez R, Ontaneda D, Buchalter RB. Geographic Disparities in Access to Neurologists and Multiple Sclerosis Care in the United States. Neurology. 2024;102(2):e207916. doi:10.1212/WNL.0000000000207916
Shoag J, Rotz SJ, Hanna R, Buhtoiarov I, Dewey EN, Bruckman D, Hamilton BK. Disparities in access to hematopoietic cell transplant persist at a transplant center. Bone Marrow Transplant. 2024 Jun 13. doi: 10.1038/s41409-024-02327-x. Epub ahead of print. PMID: 38871963.
Weleff, J., Anand, A., Dewey, E. N., & Barnett, B. S. (2024). LSD use in the United States: Examining user demographics and their evolution from 2015–2019. Journal of Psychedelic Studies (published online ahead of print 2024).
Wilkerson AD, Gentle C, Sajankila N, Dewey E, Buchalter RB, Borawski E, Strong A, Asfaw S, Wilson R, Aminian A. Association of geospatial disparities in food security with weight loss and nutritional outcomes of metabolic surgery. Surg Endosc. 2024. In press.
Becerril A, Pfoh ER, Hashmi AZ, Mourany L, Gunzler DD, Berg KA, Krieger NI, Krishnan K, Moore SE, Kahana E, Dawson NV, Luezas Shamakian L, Campbell JW, Perzynski AT, Dalton JE. Racial, ethnic and neighborhood socioeconomic differences in incidence of dementia: A regional retrospective cohort study. J Am Geriatr Soc. 2023 Mar 16. doi: 10.1111/jgs.18322. Epub ahead of print. PMID: 36928611.
Brian S. Barnett, Akhil Anand, Elizabeth N. Dewey et al. Perceived risk of LSD use in the United States from 2015-2019: Are Americans assessing LSD's risk profile more favorably?, 17 April 2023, PREPRINT (Version 2) available at Research Square [https://doi.org/10.21203/rs.3.rs-2667155/v2]
Busch RM, Dalton JE, Jehi L, Ferguson L, Krieger NI, Struck AF, Hermann BP. Association of Neighborhood Deprivation With Cognitive and Mood Outcomes in Adults With Pharmacoresistant Temporal Lobe Epilepsy. Neurology. 2023 Jun 6;100(23):e2350-e2359.
Dalton JE, Gunsalus PR, Lehr CJ, Rose J, Udeh BL, Valapour M. Incorporating Effects of Time Accrued on the Waiting List into Lung Transplantation Survival Models. Am J Respir Crit Care Med. 2023 Sep 28. doi: 10.1164/rccm.202306-0968OC. Epub ahead of print. PMID: 37771035.
Dalton JE, Lehr CJ, Gunsalus PR, Mourany L, Valapour M. Miscalibration of lung allocation models leads to inaccurate waitlist mortality predictions. Am J Transplant. 2023 Jan;23(1):72-77. doi: 10.1016/j.ajt.2022.11.012. PMID: 36695624; PMCID: PMC10016684.
Dalton JE, Lehr CJ, Gunsalus PR, Mourany L, Valapour M. Refining the Lung Allocation Score Models Fails to Improve Discrimination Performance. Chest. 2023 Jan;163(1):152-163. doi: 10.1016/j.chest.2022.08.2217. Epub 2022 Aug 27. PMID: 36030838; PMCID: PMC9899637.
Huml AM, Bilen Y, Arrigain S, Buchalter RB, Schold JD. Relationship of Social Deprivation Among Living Kidney Donor-Recipient Pairs. Transplantation Direct (in press).
Lehr CJ, Valapour M, Gunsalus PR, McKinney WT, Berg KA, Rose J, Dalton JE. Association of Socioeconomic Position With Racial and Ethnic Disparities in Survival After Lung Transplant. JAMA Netw Open. 2023 Apr 3;6(4):e238306. doi: 10.1001/jamanetworkopen.2023.8306. PMID: 37074716; PMCID: PMC10116361.
McGinley MP, Harvey T, Lopez R, Ontaneda D, Buchalter RB. Geographic disparities in access to neurologists and multiple sclerosis care in the United States. Neurology (in press).
Ramanathan, D., Bruckman, D., Appachi, S. and Hopkins, B. (2023), Association of Discharge Location Following Pediatric Tracheostomy with Social Determinants of Health: A National Analysis. Otolaryngol Head Neck Surg. https://doi.org/10.1002/ohn.516
Schold JD, Huml AM, Husain SA, Poggio ED, Buchalter RB, Lopez R, Kaplan B, Mohan S, Deceased Donor Kidneys from Higher Distressed Communities are Significantly Less Likely to be Utilized for Transplantation. American Journal of Transplantation. https://doi.org/10.1016/ j.ajt.2023.03.019
Shahnawaz Amdani, Rocio Lopez, Jesse D. Schold, W.H. Wilson Tang, 30- and 60-Day Readmission Rates for Children With Heart Failure in the United States, JACC: Heart Failure, 2023, ISSN 2213-1779, https://doi.org/10.1016/j.jchf.2023.08.029
Wolfe, M. B., Williams, T. J., Dewey, E. N., Mitchell, J. E., Pomp, A., & Wolfe, B. M. (2023). Health change awareness and its association with weight loss following bariatric surgery. Health Psychology. Advance online publication. https://doi.org/10.1037/hea0001279
Abbatemarco, Justin, “Association of Socioeconomic Disadvantage and Neighborhood Disparities with Clinical Outcomes in Multiple Sclerosis Patients” in Multiple Sclerosis and Related Disorders MSARD-D-21-01289R1
Brant AR, Batur P, Arrigain S, Lopez R, Farrell RM. Out-of-Pocket Expenditures for Contraceptives During State Medicaid Expansion, 2013-2016. Obstet Gynecol. 2022 Mar 10;. doi: 10.1097/AOG.0000000000004721. [Epub ahead of print] PubMed PMID: 35271550.
Buchalter RB, Huml AM, Poggio ED, Schold JD. Geographic hot spots of kidney transplant candidates wait-listed post-dialysis. Clinical Transplantation. e14821. doi:10.1111/ctr.14821
Chiyaka ET, Lanese B, Bruckman D, et al. Influence of interaction between community health workers and adults with chronic diseases on risk mitigation through care coordination. International Journal of Care Coordination. April 2022. doi:10.1177/20534345221092515
DeWitt-Foy, M. E., Gao, T., Schold, J., & Abouassaly, R. (2022). Stones and moans: Higher number of nephrolithiasis related encounters increases the odds of opioid misuse. Urology, doi:10.1016/j.urology.2021.09.023
Kim S, Wang PR, Lopez R, Valentim C, Muste J, Russell M, Singh RP, Phelan MP. Characterization of ophthalmic presentations to emergency departments in the United States: 2010-2018. Am J Emerg Med. 2022 Feb 22;54:279-286. doi: 10.1016/j.ajem.2022.02.024. [Epub ahead of print] PubMed PMID: 35227958.
King, K. L., Husain, S. A., Perotte, A., Adler, J. T., Schold, J. D., & Mohan, S. (2022). Deceased donor kidneys allocated out of sequence by organ procurement organizations. American Journal of Transplantation, doi:10.1111/ajt.16951
Klein SK, Brown CB, Ostrowski-Delahanty S, Bruckman D, Victorio MC. Identifying Migraine Phenotype Post Traumatic Headache (MPTH) to Guide Overall Recovery From Traumatic Brain Injury. Journal of Child Neurology. 2022;37(7):624-632. doi:10.1177/08830738221100327
Lee, I., Schold, J.D., Hehir, M.K., Claytor, B., Silvestri, N., Li, Y. Validation of myasthenia gravis diagnosis in the older Medicare population (2022) Muscle and Nerve,
Macmurdo, M., Lopez, R., Udeh,B.L., Zein,J. Beyond tobacco – the secondary impact of substance misuse in chronic obstructive lung disease (2022) Journal of Asthma, 59 (2), pp.223-229
Man S, Bruckman D, Tang AS, Uchino K, Schold J. The Association of Socioeconomic Status and Discharge Destination with 30-day Readmission after Ischemic Stroke. J Stroke Cerebrovasc Dis. 2021; 30 (12): 106146. PMID: 34644664
Mohan, S., & Schold, J. D. (2022). Accelerating deceased donor kidney utilization requires more than accelerating placement. American Journal of Transplantation, 22(1), 7-8. doi:10.1111/ajt.16866
Parikh, M.P., Garg, R., Chittajallu, V., Gupta, N., Sarvepalli, S., Lopez, R., Thota, P.N., Siddiki, H., Bhatt, A., Chahal, P., Jang, S., Stevens, T., Vargo, J., McCullough, A., Sanaka, M.R. Correction to: Trends and risk factors for 30‑day readmissions in patients with acute cholangitis: analysis from the national readmission database (Surgical Endoscopy, (2021), 35, 1, (223-231), 10.1007/s00464-020-07384-z)
(2022) Surgical Endoscopy, 36 (3), p. 2220.
R. Blake Buchalter, Suneel D. Kamath, Kanika G. Nair, David Liska, Alok A. Khorana, Stephanie L. Schmit. Novel hot and cold spots of young-onset colorectal cancer mortality in United States counties Gastroenterology, June 18, 2022
Saeed, F., Murad, H. F., Wing, R. E., Li, J., Schold, J. D., & Fiscella, K. A. (2022). Outcomes following in-hospital cardiopulmonary resuscitation in people receiving maintenance dialysis. Kidney Medicine, 4(1) doi:10.1016/j.xkme.2021.08.014
Siuba, M.T., Divyajot Sadana, Shruti Gadre, David Bruckman, Abhijit Duggal (2022)
Acute respiratory distress syndrome readmissions: A nationwide cross-sectional analysis of epidemiology and costs of care. PLoS One. 2022 Jan 25;17(1):e0263000.
Abbatemarco, J. R., Cohen, J. A., Udeh, B. L., Bassi, S., & Rensel, M. R. (2021). Multiple sclerosis wellness shared medical appointment model A pilot study. International Journal of MS Care, 23(5), 229-233. doi:10.7224/1537-2073.2020-044
Agarwal, D., Udeh, B., Campbell, J., Bena, J., & Rachitskaya, A. (2021). Follow-up appointment delay in diabetic macular edema patients. Ophthalmic Surgery Lasers and Imaging Retina, 52(4), 200-206. doi:10.3928/23258160-20210330-04
Amdani S, Boyle G, Rossano J, Scheel J, Richmond M, Arrigain S, Schold JD (2021). "Association of low center performance evaluations and pediatric heart transplant center behavior in the United States." Journal of Heart and Lung Transplantation, 40(8), 831-840. https://doi.org/10.1016/J.HEALUN.2021.04.008.
Augustine, J. J., Arrigain, S., Mandelbrot, D. A., Schold, J. D., & Poggio, E. D. (2021). Factors associated with residual kidney function and proteinuria after living kidney donation in the united states. Transplantation, , 372-381. doi:10.1097/TP.0000000000003210
Braun, W. E., Herlitz, L., Li, J., Schold, J., Poggio, E., Stephany, B., . . . Nakamoto, S. (2021). Continuous function of 80 primary renal allografts for 30–47 years with maintenance prednisone and azathioprine/mycophenolate mofetil therapy: A clinical mosaic of long-term successes. Clinical Transplantation, 35(1) doi:10.1111/ctr.14131
Bury, C., DeChicco, R., Nowak, D., Lopez, R., He, L., Jacob, S., . . . Cresci, G. (2021). Use of bedside ultrasound to assess muscle changes in the critically ill surgical patient. Journal of Parenteral and Enteral Nutrition, 45(2), 394-402. doi:10.1002/jpen.1840
Chen, D. P., Zaky, Z. S., Schold, J. D., Herlitz, L. C., El-Rifai, R., Drawz, P. E., . . . Sedor, J. R. (2021). Podocyte density is reduced in kidney allografts with high-risk APOL1 genotypes at transplantation. Clinical Transplantation, 35(4) doi:10.1111/ctr.14234
Cholin, L., Ashour, T., Mehdi, A., Taliercio, J. J., Daou, R., Arrigain, S., . . . Nakhoul, G. N. (2021). Proton-pump inhibitor vs. H2-receptor blocker use and overall risk of CKD progression. BMC Nephrology, 22(1) doi:10.1186/s12882-021-02449-0
Demkowicz R, Thota PN, Benjamin T, Lopez R, Lu H, Patil DT, Downs-Kelly E, Jeung JA, Lai KK, Lapinski J, Savage EC, Goldblum JR, Gordon IO (2021). "Allaying uncertainty in diagnosing buried Barrett's esophagus." Annals of Diagnostic Pathology, 51. https://doi.org/10.1016/J.ANNDIAGPATH.2020.151672.
Gill, J. S., Schold, J., & Kaplan, B. (2021). Understanding risks and our responsibility to living donors. Journal of the American Society of Nephrology, 32(11), 2691-2693. doi:10.1681/ASN.2021081129
Hertle RW, Kelleher C, Bruckman D, McNinch N, Ricker I, Bouhenni R, Wiseman K (2021). "Analysis of anomalous head posturing in patients with infantile nystagmus syndrome." Journal of AAPOS, 25(3), 145.e1-145.e5. https://doi.org/10.1016/J.JAAPOS.2021.02.009.
Hsu, C. M., Murad, H., Neuendorf, K., Gao, T., Schold, J. D., & Saeed, F. (2021). Outcomes of palliative care consultation in patients with ESRD who received cardiopulmonary resuscitation. Clinical Nephrology, 96(1), 22-28. doi:10.5414/CN110096
Huml, A. M., Sedor, J. R., Poggio, E., Patzer, R. E., & Schold, J. D. (2021). An opt-out model for kidney transplant referral: The time has come. American Journal of Transplantation, 21(1), 32-36. doi:10.1111/ajt.16129
Huml AM, Schold JD (2021). "Kidney Transplantation and Candidate BMI: Viability Is in the Eye of the Beholder." American Journal of Kidney Diseases, 78(4), 484-486. https://doi.org/10.1053/J.AJKD.2021.04.005.
Husain SA, King KL, Sanichar N, Crew RJ, Schold JD, Mohan S (2021). "Association between Donor-Recipient Biological Relationship and Allograft Outcomes after Living Donor Kidney Transplant." JAMA Network Open. https://doi.org/10.1001/JAMANETWORKOPEN.2021.5718.
Kim RJ, Lopez R, Snair M, Tang A (2021). "Mediterranean diet adherence and metabolic syndrome in US adolescents." International Journal of Food Sciences and Nutrition, 72(4), 537-547. https://doi.org/10.1080/09637486.2020.1840533.
Klein, E. A., Li, J., Milinovich, A., Schold, J. D., Sharifi, N., Kattan, M. W., & Jehi, L. (2021). Androgen deprivation therapy in men with prostate cancer does not affect risk of infection with SARS-CoV-2. The Journal of Urology, 205(2), 441-443. doi:10.1097/JU.0000000000001338
Kumar S, Lin S, Schold JD (2021). "Impact of donation after circulatory death donor allografts on outcomes following liver transplantation for fulminant hepatic failure in the United States." American Journal of Transplantation, 21(1), 382-390. https://doi.org/10.1111/AJT.16286.
Lentobarros, D., Karp, S., Simon, G. J., Pruett, T., Schold, J., & Pruinelli, L. (2021). Disparity in access to care impacts liver transplant mortality doi:10.3233/SHTI210706 Retrieved from www.scopus.com
Li, M. T., King, K. L., Husain, S. A., Schold, J. D., & Mohan, S. (2021). Deceased donor kidneys utilization and discard rates during COVID-19 pandemic in the united states. Kidney International Reports, 6(9), 2463-2467. doi:10.1016/j.ekir.2021.06.002
Lopez, R., Snair, M., Arrigain, S., Schold, J. D., Hustey, F., Walker, L. E., & Phelan, M. P. (2021). Sex-based differences in timely emergency department evaluations for patients with drug poisoning. Public Health, 199, 57-64. doi:10.1016/j.puhe.2021.08.011
Mayne, T. J., Nordyke, R. J., Schold, J. D., Weir, M. R., & Mohan, S. (2021). Defining a minimal clinically meaningful difference in 12-month estimated glomerular filtration rate for clinical trials in deceased donor kidney transplantation. Clinical Transplantation, 35(7) doi:10.1111/ctr.14326
MacMurdo M, Lopez R, Udeh BL, Zein JG (2021). "Alcohol use disorder and healthcare utilization in patients with chronic asthma and obstructive lung disease." Alcohol, 93, 11-16. https://doi.org/10.1016/J.ALCOHOL.2021.03.002.
Man S, Bruckman D, Tang AS, Uchino K, Schold JD (2021). "The Association of Socioeconomic Status and Discharge Destination with 30-Day Readmission after Ischemic Stroke." Journal of Stroke and Cerebrovascular Diseases, 30(12), 106146. https://doi.org/10.1016/J.JSTROKECEREBROVASDIS.2021.106146.
Mohan, S., King, K. L., Husain, S. A., & Schold, J. D. (2021). COVID-19–associated mortality among kidney transplant recipients and candidates in the united states. Clinical Journal of the American Society of Nephrology, 16(11), 1695-1703. doi:10.2215/CJN.02690221
Mohan S, Schold JD (2021). "Accelerating deceased donor kidney utilization requires more than accelerating placement." American Journal of Transplantation. https://doi.org/10.1111/AJT.16866.
Mehta, N., Abushahin, A., Sadaps, M., Alomari, M., Vargo, J., Patil, D., . . . Bhatt, A. (2021). Recurrence with malignancy after endoscopic resection of large colon polyps with high-grade dysplasia: Incidence and risk factors. Surgical Endoscopy, 35(6), 2500-2508. doi:10.1007/s00464-020-07660-y
Monachese, M., Lee, P., Harris, K., Jang, S., Bhatt, A., Chahal, P., . . . Stevens, T. (2021). EUS and secretin endoscopic pancreatic function test predict evolution to overt structural changes of chronic pancreatitis in patients with nondiagnostic baseline imaging. Endoscopic Ultrasound, 10(2), 116-123. doi:10.4103/2303-9027.313801
Monachese, M., Mankaney, G., El-Khider, F., Rouphael, C., Lopez, R., & Burke, C. A. (2021). Association between baseline hyperplastic polyps and metachronous serrated lesions. Gastrointestinal Endoscopy, 93(6), 1401-1407.e1. doi:10.1016/j.gie.2020.11.0286
Mummadi SR, Stoller JK, Lopez R, Kailasam K, Gillespie C, Hahn PY (2021). "Epidemiology of Adult Pleural Disease in the United States." Chest, 160(4), 1534-1551. https://doi.org/10.1016/J.CHEST.2021.05.026.
Nakhoul, G. N., Mehdi, A., Taliercio, J. J., Arrigain, S., Schold, J. D., Spencer, A., . . . Bierer, S. B. (2021). "What do you think about nephrology?" A national survey of internal medicine residents. BMC Nephrology, 22(1) doi:10.1186/s12882-021-02397-9
Navaneethan SD, Kirwan JP, Remer EM, Schneider E, Addeman B, Arrigain S, Horwitz E, Fink JC, Lash JP, McKenzie CA, Rahman M, Rao PS, Schold JD, Shafi T, Taliercio JJ, Townsend RR, Feldman HI, Appel LJ, Go AS, He J, Nelson RG, Shah VO, Unruh ML, Sondheimer JH (2021). "Adiposity, Physical Function, and Their Associations With Insulin Resistance, Inflammation, and Adipokines in CKD." American Journal of Kidney Diseases, 77(1), 44-55. https://doi.org/10.1053/J.AJKD.2020.05.028.
Parikh, M. P., Garg, R., Chittajallu, V., Gupta, N., Sarvepalli, S., Lopez, R., . . . Sanaka, M. R. (2021). Trends and risk factors for 30-day readmissions in patients with acute cholangitis: Analysis from the national readmission database. Surgical Endoscopy, 35(1), 223-231. doi:10.1007/s00464-020-07384-z
Park C, Clemenceau JR, Seballos A, Crawford S, Lopez R, Coy T, Atluri G, Hwang TH (2021). "A spatiotemporal analysis of opioid poisoning mortality in Ohio from 2010 to 2016." Scientific Reports, 11(1). https://doi.org/10.1038/S41598-021-83544-Y.
Poggio ED, Augustine JJ, Arrigain S, Brennan DC, Schold JD (2021). "Long-term kidney transplant graft survivalâ€"Making progress when most needed." American Journal of Transplantation, 21(8), 2824-2832. https://doi.org/10.1111/AJT.16463.
Pruinelli, L., Zhou, J., Stai, B., Schold, J. D., Pruett, T., Ma, S., & Simon, G. (2021). A likelihood-based convolution approach to estimate major health events in longitudinal health records data: An external validation study. Journal of the American Medical Informatics Association, 28(9), 1885-1891. doi:10.1093/jamia/ocab087
Rouphael C, Lopez R, McMichael J, Burke CA (2021). "≥3 Nonadvanced Adenomas are More Common in the Era of Contemporary Colonoscopy and Not Associated with Metachronous Advanced Neoplasia." Journal of Clinical Gastroenterology, 55(4), 343-349. https://doi.org/10.1097/MCG.0000000000001364.
Sanaka, M. R., Khoudari, G., Parikh, M., Thota, P. N., Lopez, R., Gupta, N., . . . Raja, S. (2021). Peroral endoscopic myotomy is highly effective for achalasia patients with recurrent symptoms after pneumatic dilatation. Surgical Endoscopy, 35(6), 2965-2975. doi:10.1007/s00464-020-07737-8
Sanghi, V., Romero-Marrero, C., Flocco, G., Graham, R. P., Abduljawad, B., Niyazi, F., . . . Allende, D. S. (2021). The spectrum of histopathological findings after SVR to DAA for recurrent HCV infection in liver transplant recipients. Virchows Archiv, doi:10.1007/s00428-021-03191-6
Schold JD (2021). "Shifting transplant center performance evaluations upstream." American Journal of Transplantation, 21(1), 7-8. https://doi.org/10.1111/AJT.16335.
Schold JD, Augustine JJ, Huml AM, Fatica R, Nurko S, Wee A, Poggio ED (2021). "Effects of body mass index on kidney transplant outcomes are significantly modified by patient characteristics." American Journal of Transplantation, 21(2), 751-765. https://doi.org/10.1111/AJT.16196.
Schold JD, King KL, Husain SA, Poggio ED, Buccini LD, Mohan S (2021). "COVID-19 mortality among kidney transplant candidates is strongly associated with social determinants of health." American Journal of Transplantation, 21(7), 2563-2572. https://doi.org/10.1111/AJT.16578.
Schold JD, Mohan S (2021). "A deeper dive into the impact of multiple-organ transplant policy on kidney transplant candidate prognoses." American Journal of Transplantation, 21(6), 2004-2006. https://doi.org/10.1111/AJT.16508.
Schold JD, Mohan S, Huml A, Buccini LD, Sedor JR, Augustine JJ, Poggio ED (2021). "Failure to Advance Access to Kidney Transplantation over Two Decades in the United States." Journal of the American Society of Nephrology, 32(4), 913-926. https://doi.org/10.1681/ASN.2020060888.
Schold, J. D., Huml, A. M., Poggio, E. D., Sedor, J. R., Husain, S. A., King, K. L., & Mohan, S. (2021). Patients with high priority for kidney transplant who are not given expedited placement on the transplant waiting list represent lost opportunities. Journal of the American Society of Nephrology, 32(7), 1733-1746. doi:10.1681/ASN.2020081146
Simons-Linares, C. R., Abushamma, S., Romero-Marrero, C., Bhatt, A., Lopez, R., Jang, S., . . . Chahal, P. (2021). Clinical outcomes of acute pancreatitis in patients with cirrhosis according to liver disease severity scores. Digestive Diseases and Sciences, 66(8), 2795-2804. doi:10.1007/s10620-020-06575-x
Singh A, Garg R, Lopez R, Alkhouri N (2021). "Diabetes Liver Fibrosis Score to Detect Advanced Fibrosis in Diabetics with Nonalcoholic Fatty Liver Disease." Clinical Gastroenterology and Hepatology. https://doi.org/10.1016/J.CGH.2021.01.010.
Solanki N., Bruckman D., Tang A.S., Khatri S.B. Air Quality Data for Nitrogen Dioxide and Pediatric Hospital Admission Rates in Selected Cities. Am. J. Respir. Crit. Care Med. 2021; 203(9): no pagination. doi:10.1164/ajrccm-conference MeetingAbstracts.A3171
Thota, P. N., Malik, S., Shakya, S., AnilKumar, M., Gabbard, S., Sanaka, M. R., . . . Lopez, R. (2021). Changes in esophageal physiology after paraesophageal hernia repair and collis gastroplasty. Esophagus, 18(2), 339-345. doi:10.1007/s10388-020-00766-1
Tsuang WM, Arrigain S, Lopez R, Budev M, Schold JD (2021). "Lung transplant waitlist outcomes in the United States and patient travel distance." American Journal of Transplantation, 21(1), 272-280. https://doi.org/10.1111/AJT.16193.
Uffing, A., Pérez-Saéz, M. J., Jouve, T., Bugnazet, M., Malvezzi, P., Muhsin, S. A., . . . Riella, L. V. (2021). Recurrence of iga nephropathy after kidney transplantation in adults. Clinical Journal of the American Society of Nephrology, 16(8), 1247-1255. doi:10.2215/CJN.00910121
Wang PR, Lopez R, Seballos SS, Campbell MJ, Udeh BL, Phelan MP (2021). "Management of migraine in the emergency department: Findings from the 2010â€"2017 national hospital ambulatory medical care surveys." American Journal of Emergency Medicine, 41, 40-45. https://doi.org/10.1016/J.AJEM.2020.12.056.
Wood, A., Eghtesad, B., Menon, K. V. N., Fares, M., Tong, M. Z. -., Sharma, V., . . . Modaresi Esfeh, J. (2021). Safety and outcomes of combined liver transplantation and cardiac surgery in cirrhosis. Annals of Thoracic Surgery, 111(1), 62-68. doi:10.1016/j.athoracsur.2020.04.135
Zhang P, Lopez R, Arrigain S, Rath M, Khatri SB, Zein JG (2021). "Dietary patterns in patients with asthma and their relationship with asthma-related emergency room visits: NHANES 2005â€"2016." Journal of Asthma, 1-9. https://doi.org/10.1080/02770903.2021.1984529.
Zhang P, Lopez R, Attaway AH, Georas SN, Khatri SB, Abi-Saleh S, Zein JG (2021). "Diabetes Mellitus Is Associated with Worse Outcome in Patients Hospitalized for Asthma." Journal of Allergy and Clinical Immunology: In Practice, 9(4), 1562-1569.e1. https://doi.org/10.1016/J.JAIP.2020.10.054.
Znidarsic J, Kirksey KN, Dombrowski SM, Tang A, Lopez R, Blonsky H, Todorov I, Schneeberger D, Doyle J, Libertini L, Jamie S, Segall T, Bang A, Barringer K, Judi B, Ehrman JP, Roizen MF, Golubic M (2021). ""Living Well with Chronic Pain": Integrative Pain Management via Shared Medical Appointments." Pain medicine (Malden, Mass.), 22(1), 181-190. https://doi.org/10.1093/PM/PNAA418.
Znidarsic J, Kirksey KN, Dombrowski SM, Tang A, Lopez R, Blonsky H, Todorov I, Schneeberger D, Doyle J, Libertini L, Starkey J, Segall T, Bang A, Barringer K, Bar J, Ehrman JP, Roizen MF, Golubic M (2021). "Corrigendum to: Living Well with Chronic Pain: Integrative Pain Management via Shared Medical Appointments." Pain Medicine https://doi.org/10.1093/PM/PNAB145.
2022 Symposium
The Center for Populations Health Research presented a symposium in partnership with the Cleveland Clinic Healthcare Delivery and Implementation Science Center entitled "Implementing Evidence into Practice: Using Data to Improve Quality of Care." Attendees explored how the fields of Population Health and Implementation Science Research can provide methods to capture data about clinical context and outcomes and optimally align with improving care delivery systems and the quality of clinical care. Watch a recording of the event.
2022 Abstracts and Presentations
Blake Buchalter, PhD received the Young Investigator Award from the American Transplant Congress. His recent publication: “Racial Hot Spots Of Non-preemptive Kidney Transplant Waitlisting, 2010-2020” offers significant insight into the kidney transplant waitlist. He will present an oral talk at the American Transplant Congress (ATC) 2022 Meeting in June.
Reena Mehra had a poster presentation at SLEEP 2022 Conference Pena Orbea C, Bruckman D, Foldvary N, Kazaglis L, Alberts J, Mehra R “Elucidating Sleep-Related Health Disparities across The Socioeconomic Spectrum Leveraging a Large-Scale Sleep Registry”
Bruckman D, Schold JD. Significantly Increased Mental Health Disorders and Inadequate Housing Among Pediatric Inpatients in the United States. (poster). AcademyHealth 2022 Annual Research Meeting, Washington, DC; June 4-7,2022
Core Team
The Center for Populations Health Research (CPHR) is comprised of members from across the Cleveland Clinic enterprise, spanning diverse backgrounds and expertise. We encourage members to contribute insights regarding emerging research and clinical practice, as well as various experiences with different types of patient populations. An Aim of CPHR is to provide a nexus for investigators conducting population health research across institutions to interact and collaborate.