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Philippe Haouzi Laboratory

❮Neurosciences Philippe Haouzi Laboratory
  • Philippe Haouzi Laboratory
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Principal Investigator

Philippe Haouzi Headshot

Philippe Haouzi, MD, PhD

Staff
Location: Cleveland Clinic Main Campus

Research

The Haouzi Laboratory is an NIH funded laboratory of physiology that specializes in the study of fundamental mechanisms regulating breathing and circulation and their implications in specific life-threatening conditions produced by severe hypoxia, created by an opioid overdose, circulatory shock or mitochondrial poisons. The research is using in vivo models which are developed to mimic as much as possible realistic clinical situations. 


Biography

Dr. Haouzi is a researcher and a staff physician in the Department of Pulmonary Medicine at Cleveland Clinic. He is the current medical director for the Cleveland Clinic’s Pulmonary Function Testing laboratories. He is an international expert in respiratory physiology. He has authored or co-authored more than 130 publications. 


Education & Professional Highlights

 9/1996 - present Tenured Professor of Physiology and Medicine

                             Université H. Poincaré, Nancy, Faculté de Médecine de Nancy, France

7/2000 - 7/2007   Director, Research Group EA 4350

                             Université H. Poincaré, Faculté de Médecine Nancy, Laboratoire de Physiologie, de Nancy

9/2002 - 7/2007   Division Chief, Department of Pulmonary Medicine

                             University Hospital of Nancy, France

7/2007 - 12/2022  Tenured Professor of Medicine

                              Pennsylvania State University College of Medicine, Hershey, PA

                              Attending Physician, Division of Pulmonary and Critical Care Medicine

                              PennState Hershey Medical Center

12/2022 - present  Staff Physician, Division of Pulmonary and Critical Care Medicine

                               Cleveland Clinic

12/2022 - present  Medical Director, Pulmonary Function testing labs

                               Director, Respiratory Physiology program

                               Department of Pulmonary Medicine, Respiratory Institute

                               Cleveland Clinic

3/2024 - present    Professor of Medicine

                               Case Western Reserve University, Lerner School of Medicine 

 

Awards

NATO scholarship for senior scientist, "Chercheur confirmé, 1997.  

Fellow of the Japanese Society for the Promotion of Science (JSPS), 2002.  

Laureat de l’Académie Nationale de Médecine: Grand Prix Jansen de l’Académie Nationale de Médecine, 2003.  

Exceptional Clinician Performance Award, Department of Medicine, PennState Hershey Medical Center, 2021. 

 

Current memberships and main services since 2012

· Member of the Promotion & Tenure Committee, Dept of Medicine, Pennsylvania State University, College of Medicine (since 2014)

· Member of the Research Advisory Committee, Dept of Medicine, Pennsylvania State University, College of Medicine

· Member of the American Physiological Society (since 1995)

· Member of the American Thoracic Society (since 2001)

· Referee:  Journal of Applied Physiology, European Journal of Applied Physiology, American Journal of Physiology, Respiratory Physiology and Neurobiology, Pediatric research, Canadian journal of Applied Physiology, Experimental Physiology, Critical Care Medicine, Chest. Editorial board: Journal of Applied Physiology

· Ad-Hoc referee for vaious NIH study sections : 05/2017 ZRG1 MDCN-B(54), 08 /2017 ZRG1 MDCN-B(55), 01/2018 ZRG1 F10A-A(20), 05/ 2018 ZRG1 MDCN-B(50), 05/2018ZRG1 MDCN-B(54), 01/2019ZRG1 F10A-R(20), /05/2021ZRG1 MDCN-B(54), 05/2021ZRG1 MDCN-B(50), 05/022ZDA1 PXN-F (12), 05/2022 ZRG1 DKUS-P (50), 01/2023 ZRG1 KUDS-F (54)

· Underserved Clinics Volunteer attending at the LionCare Clinic, Harrisburg, PA (Sept. 2017 to 2022) LionCare is a non-profit, free clinic dedicated to  serving the medical needs of Harrisburg's underserved population. 

Research

Research

1. Over the last 3 decades, our laboratory has led to the development of new theories on the regulation of respiration and blood gas homeostasis, based upon neural coupling between breathing, circulation and metabolism.

2. We have in parallel to this thematic developed NIH funded research programs related to various conditions leading or related to hypoxia such as the mechanisms of lethality following an opioid overdose and treatment, the effects of cytotoxic hypoxia during mitochondrial intoxication (cyanide or H2S) or the effects of tissular hypoxia produced during circulatory failure. We have, combined to mechanistic studies, a program on the development of countermeasures.

One of the specificities of our research is to use models which are as close as possible to clinically-relevant conditions, to understand the pathophysiology and treatment of life-threatening conditions related to hypoxia. 

Our Team

Our Team

Publications

Selected Publications

View publications for Philippe Haouzi, MD, PhD
(Disclaimer: This search is powered by PubMed, a service of the U.S. National Library of Medicine. PubMed is a third-party website with no affiliation with Cleveland Clinic.)


Careers

Careers

Training at Lerner Research Institute

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