Jean-Paul Achkar, MD
Staff
Location: Cleveland Clinic Main Campus
Research
Dr. Achkar's research interests span translational IBD genetics studies and clinical projects studying the pathogenesis of IBD, its clinical manifestations and associated complications.
Biography
Jean-Paul Achkar, MD, is a Staff Physician in the Department of Gastroenterology of the Digestive Disease Center, located on the main campus of Cleveland Clinic. From 2002 to 2007, he served as Director of the Cleveland Clinic Gastroenterology Fellowship Program. He is certified in gastroenterology by the National Board of Examiners, and his specialty interests include Crohn's disease and ulcerative colitis.
Dr. Achkar received his medical degree from Case Western Reserve University School of Medicine. He also conducted his internship and residency in internal medicine at University Hospitals of Cleveland/Case Western Reserve University, where he served as Chief Resident in Internal Medicine. He then went on to conduct his fellowship in gastroenterology and hepatology at the University of Pittsburgh Medical Center, where he was Chief Fellow.
He is principal or co-investigator in several research trials that have been published in leading peer-reviewed journals. He has also contributed chapters to several medical textbooks in his field. He is the recipient of research awards from the National Institutes of Health (NIH), Cleveland Clinic, GlaxoSmithKline Institute for Digestive Health and the American College of Gastroenterology.
Dr. Achkar has also received the Physician of the Year Award from the Gastroenterology Department of Cleveland Clinic, the Crohn’s and Colitis Foundation of America Premier Physician Award, two Senior Fellow Teaching Awards, and the American College of Gastroenterology Governors Award for Best Scientific Paper. He is a member of the American College of Gastroenterology, the American Gastroenterological Association, and the Crohn’s and Colitis Foundation of America.
Education & Professional Highlights
Education & Fellowships
Fellowship - University of Pittsburgh Medical Center
Gastroenterology & Hepatology
Pittsburgh, PA USA
1998
Residency - University Hospitals of Cleveland
Internal Medicine
Cleveland, OH USA
1995
Internship - University Hospitals of Cleveland
Internal Medicine
Cleveland, OH USA
1992
Medical Education - Case Western Reserve University School of Medicine
Cleveland, OH USA
1991
Undergraduate - Tufts University
Biology and French
Boston, MA USA
1987
Professional Highlights
- National Institutes of Health K23 Grant Award for Genetic Studies in Crohn’s Disease
Certifications
- Internal Medicine - Gastroenterology
Awards & Honors
- Physician of the Year Award, Gastroenterology Department, Cleveland Clinic
- Premier Physician Award, Crohn’s and Colitis Foundation of America
- Two Senior Fellow Teaching Awards
- Governors Award for Best Scientific Paper, American College of Gastroenterology
Memberships
- Chair, Educational Affairs Committee, American College of Gastroenterology
- Board member, Northeast Ohio Chapter Board of Trustees, Crohn's and Colitis Foundation of America
- American Gastroenterological Association
Research
I work both as a clinician seeing patients with complicated inflammatory bowel disease (IBD) and as a clinical and translational researcher. My research interests span translational IBD genetics studies and clinical projects studying the pathogenesis of IBD, its clinical manifestations and associated complications. From a genetics standpoint, my work has focused on identifying genetic variants associated with IBD and defining the functional significance of such IBD-associated genetic variants. I have developed an IBD DNA bank in which we have collected DNA and clinical information from 2,000 individuals (cases and controls) which has led to several publications and collaborations with other groups.
Our Team
Selected Publications
View publications for Jean-Paul Achkar, MD
(Disclaimer: This search is powered by PubMed, a service of the U.S. National Library of Medicine. PubMed is a third-party website with no affiliation with Cleveland Clinic.)
Bachour Salam P, Shah Ravi, Rieder Florian, Qazi Taha, Achkar Jean Paul, Philpott Jessica, Lashner Bret, Holubar Stefan D, Lightner Amy L, Regueiro Miguel, Click Benjamin, Cohen Benjamin L. Intraabdominal septic complications after ileocolic resection increases risk for endoscopic and surgical postoperative Crohn's disease recurrence. 2022. 35705188.
Kurowski Jacob A, Achkar Jean-Paul, Sugano David, Milinovich Alex, Ji Xinge, Bauman Janine, Griffin Keyonna R, Kattan Michael W. Computable Phenotype of a Crohn's Disease Natural History Model. 2022. 35658747.
Bachour Salam P, Shah Ravi S, Lyu Ruishen, Rieder Florian, Qazi Taha, Lashner Bret, Achkar Jean Paul, Philpott Jessica, Holubar Stefan D, Lightner Amy L, Regueiro Miguel, Cohen Benjamin L, Click Benjamin H. Mild neoterminal ileal post-operative recurrence of Crohn's disease conveys higher risk for severe endoscopic disease progression than isolated anastomotic lesions. 2022. 35285534.
Bachour Salam P, Shah Ravi S, Lyu Ruishen, Rieder Florian, Cohen Benjamin, Qazi Taha, Lashner Bret, Achkar Jean Paul, Philpott Jessica, Holubar Stefan D, Lightner Amy L, Regueiro Miguel, Baker Mark E, Click Benjamin. Test Characteristics of Cross-sectional Imaging and Concordance With Endoscopy in Postoperative Crohn's Disease. 2022. 34968729.
Holubar Stefan D, Gunter Rebecca L, Click Benjamin H, Achkar Jean-Paul, Lightner Amy L, Lipman Jeremy M, Hull Tracy L, Regueiro Miguel, Rieder Florian, Steele Scott R. Mesenteric Excision and Exclusion for Ileocolic Crohn's Disease: Feasibility and Safety of an Innovative, Combined Surgical Approach With Extended Mesenteric Excision and Kono-S Anastomosis. 2022. 34882636.
Garg Rajat, Aggarwal Manik, Butler Robert, Achkar Jean Paul, Lashner Bret, Philpott Jessica, Cohen Benjamin, Qazi Taha, Rieder Florian, Regueiro Miguel, Click Benjamin. Real-World Effectiveness and Safety of Ustekinumab in Elderly Crohn's Disease Patients. 2022. 34160735.
Faisal Muhammad Salman, Burke Carol A, Achkar Jean-Paul, Click Benjamin, O'Malley Margaret, LaGuardia Lisa, Milicia Susan, Leach Brandie, Liska David, Church James, Kalady Matthew, Mankaney Gautam. Malignancy risk in individuals with familial adenomatous polyposis receiving biologics and immunomodulators. 2022. 33822277.
Patel Priyesh, Chadalavada Pravallika, Singh Amandeep, Gurajala Ram Kishore, Achkar Jean-Paul. Accessory Splenic Artery Causing Massive Gastrointestinal Bleed. 2021. 33718509.
Shah Ravi S, Bachour Salam, Jia Xue, Holubar Stefan D, Hull Tracy L, Achkar Jean-Paul, Philpott Jessica, Qazi Taha, Rieder Florian, Cohen Benjamin L, Regueiro Miguel D, Lightner Amy L, Click Benjamin H. Hypoalbuminaemia, Not Biologic Exposure, Is Associated with Postoperative Complications in Crohn's Disease Patients Undergoing Ileocolic Resection. 2021. 33388775.
Kurowski Jacob A, Achkar Jean-Paul, Barbur Iulia, Bonfield Tracey L, Worley Sarah, Remer Erick M, Fiocchi Claudio, Viswanath Satish E, Kay Marsha H. Adipokine Resistin Levels at Time of Pediatric Crohn Disease Diagnosis Predict Escalation to Biologic Therapy. 2021. 32978938.
Kurowski Jacob A, Milinovich Alex, Ji Xinge, Bauman Janine, Sugano David, Kattan Michael W, Achkar Jean-Paul. Differences in Biologic Utilization and Surgery Rates in Pediatric and Adult Crohn's Disease: Results From a Large Electronic Medical Record-derived Cohort. 2021. 32914165.
El Ouali Sara, Achkar Jean-Paul, Lashner Bret, Regueiro Miguel. Gastrointestinal manifestations of COVID-19. 2021. 32554734.
Kurowski Jacob A, Achkar Jean-Paul. Underutilization of Combination Anti-TNF Therapy in Population-based Study. 2020. 31340027.
Achkar Jean-Paul. Tailored Medical Management of the Complex Postoperative Crohn's Disease Patient. 2019. 31275068.
Bhagya Rao Bhavana, Garber Ari, Achkar Jean-Paul. Jejunal necrosis after internal herniation of Roux limb through Petersen defect. 2019. 30959028.
Song Gengqing, Fiocchi Claudio, Achkar Jean-Paul. Acupuncture in Inflammatory Bowel Disease. 2019. 30535303.