Atherosclerosis and thrombosis: Protein factors have been identified that link hyperlipidemia, a major risk factor for atherosclerosis, and a prothrombotic state. [PubMed]
Brain tumor therapy: Potential new target involving cancer stem cells has been identified. [PubMed]
Heart disease: Link discovered between heart disease, common dietary lipid, and its gut flora-induced metabolites in plasma.[PubMed]
Thrombosis: New component of the molecular mechanism underlying the thrombotic disorder Antiphospholipid Syndrome (APS) has been identified. [PubMed]
Thrombosis and heart disease: Inherited polymorphisms at the CD36 locus causes variability in CD36 surface expression, which affects the response of platelets to oxidized LDL. This suggests that inherited variations in CD36 may influence risk of thrombosis, which contributes to heart disease. [PubMed]
Lerner Research Institute
Cleveland Clinic, Mail Code NB21
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Cleveland, Ohio 44195
