Laboratory

orloff   Mohammed Orloff, PhD is a Project Scientist in the Eng lab and he received his PhD from the Division of Genetic Epidemiology in the Department of Epidemiology and Biostatistics, Case Western Reserve University in 2005. He is studying the phenomics of PTEN alterations; non-traditional low penetrance genomic mechanisms of common cancer susceptibility; and the role of genomic and epigenomic alterations in solid tumor microenvironment as it relates to clinical outcome. Dr. Orloff also serves as a mentor for trainees in genetics and genomics in the Eng lab.
gurkan   Gurkan Bebek, PhD is a Postdoctoral Fellow in the Eng lab and the Mark Chance lab (Center for Proteomics and Mass Spectrometry, Case Western Reserve University) under the Computational Genomic Epidemiology of Cancer Training Program (NCI R25T). He received his PhD in the Department of Electrical Engineering and Computer Science at the Case Western Reserve University. Gurkan’s project entails developing new methodologies and algorithms to improve the understanding of complex biological networks as they relate to head and neck carcinogenesis.
paula   Pauline Funchain, MD is a Medical Oncology Fellow at the Taussig Cancer Institute and plans to extend her fellowship to encompass cancer genomic medicine. She received her MD and internal medicine residency at Harbor-UCLA Medical Center. She joined the Cleveland Clinic to begin her oncology fellowship in 2009.
he   Xin “Jason” He, PhD is a Postdoctoral Fellow in the Eng lab and received his doctoral degree from the University of Pittsburgh in 2008. Jason is studying intracellular PTEN trafficking in solid tumorigenesis.
judith   Judith Hobert, PhD is a Postdoctoral Fellow in the Eng lab and received her PhD from the University of Chicago in 2006. She is studying PTEN and related signaling pathways in autism and in carcinogenesis.
joanne   Joanne Ngeow, MB BS, MRCP is a Clinical Cancer Genetics Fellow in the Center for Personalized Genetic Healthcare funded by the National Medical Research Council of Singapore. She is a medical oncologist at the National Cancer Center Singapore and is here to receive basic training as an academic clinical cancer geneticist and to begin some training in clinical research.
wang   Yu Wang, PhD is a Postdoctoral Fellow in the Eng lab and received his PhD from the University of California, Davis. He is studying the role of non-coding RNA in PTEN intracellular localization and signaling in prostate and breast carcinogenesis.
ying   Ying Ni, MS is a Graduate Student in the HHMI PhD Program in Molecular Medicine, Cleveland Clinic Lerner College of Medicine. She is studying the role of SDH and PTEN in Cowden syndrome.
emz   Emily Pontzer, BS, is a MD PhD candidate in the MSTP program at Case Western Reserve University School of Medicine. She graduated from Duke University with a degree in Biology. She is studying the regulation of PTEN and related gene expression as related to heritable cancers.
amanda   Amanda Tilot, BA is a predoctoral fellow in the HHMI PhD Program in Molecular Medicine, Cleveland Clinic Lerner College of Medicine. She graduated from Albion College, MI in 2009 with a degree in Biology and Psychology. She is currently studying the genetics of autism susceptibility.
jaz   Jazmine Sutton, BS is a Medical Student in the Cleveland Clinic Lerner College of Medicine. She graduated from Duke University in 2006. Jaz is studying the role of PTEN and the 10q region in disparities in outcome of endometrial cancer in African Americans.
todd   Todd Romigh, MS is the Lab Manager and a Lead Research Technologist in the Eng lab. In addition to administrative and technical oversight of the lab, he provides rigorous and thoughtful core construct making, characterization and storage services for the Eng lab.
no pic   Fusong Chen, MS is a Senior Research Technologist whose project involves scanning PTEN and related genes in heritable cancer syndromes.
chen   Jin-Lian Chen, MS is a Senior Research Technologist in the Eng lab. Her project involves mutation scanning of SDHx in pheochromocytoma/paraganglioma and in heritable breast cancer syndromes.
charissa   Charissa Peterson, MS is a Senior Research Technologist in the Eng lab. Her project involves the genomics of common cancer susceptibility.
qi   Qi Yu, MS is a Senior Research Technologist who has charge over the Eng lab’s animal models of human disease.