The Program for Liver Disease Research (Laura Nagy, PhD, Director) in the Department of Inflammation & Immunity at Cleveland Clinic's Lerner Research Institute seeks experienced investigators who use multidisciplinary approaches to determine the underlying causes of and develop new treatments for liver diseases and/or systemic diseases that prominently involve the liver, particularly alcohol- and non-alcohol associated liver disease. Individuals must be able to communicate across fields to tackle fundamental issues in this field, and those with demonstrated potential for creativity and excellence in the fields of multi-organ physiology (liver-brain, liver-gut axes, reticulo-endothelial system as examples) or experts in targeting metabolism (genetic and environment influences), fibrosis, stem cell biology, immunology, and vascular biology are ideal candidates. Individuals with interest and experience in computational methods, -omics technologies, and use of human biospecimens in the context of liver biology are also desired.
Individuals will receive faculty appointments at the Associate or Full Staff (equivalent to Associate or Full Professor) in the Department of Inflammation and Immunity in the Lerner Research Institute and joint appointments in clinical institutes, as appropriate. New recruits will join a highly collaborative environment within the Department of Inflammation and Immunity (https://www.lerner.ccf.org/inflammation-immunity/) and the Northern Ohio Alcohol Center (https://www.lerner.ccf.org/alcoholcenter/). The successful candidate will take advantage of Liver Center expertise and biobank resources to investigate and develop new diagnostics and therapies and to mentor junior members in the Center, with opportunities for leadership growth. Cleveland Clinic provides exceptional opportunities for partnerships with basic and translational investigators, as well as with clinicians from multiple specialties. Outstanding facilities, generous start-up funds, and ongoing operational support will be provided. Research programs are supported by world class core facilities with the opportunity for growth with the substantial expansion of the Lerner Research Institute through the formation of the Global Center for Pathogen Research and Human Health.
The Lerner Research Institute, with >1800 researchers in 12 departments and an annual budget of >$400 million, has a commitment to excellence in basic, translational and clinical research, with an emphasis on interactive, collaborative research. Faculty typically also become members of the Molecular Medicine Graduate Training Program and other graduate and medical training programs at Case Western Reserve University School of Medicine, providing access to excellent Ph.D. students and postdoctoral fellows.
Candidates should submit a complete curriculum vitae and brief statement of research interests and names of 3 references by email to: Sarah Krafcik ([email protected])
Sarah Krafcik
[email protected]
The Cleveland Clinic Health System (CC) is searching for a doctoral level faculty member to join its multidisciplinary Department of Quantitative Health Sciences on the Cleveland, Ohio main campus. This is a full-time position consisting of 70% designing/analyzing clinical trials and observational studies with investigators from the CC’s Musculoskeletal Research Center and 30% independent research. A doctoral degree with expertise in biostatistics and/or epidemiology is required. The position includes a non-tenured appointment to the Cleveland Clinic Lerner College of Medicine of Case Western Reserve University at rank commensurate with experience. Candidates should enjoy collaborating on and bringing creative analytic approaches to complex problems in health care and have a strong desire to publish journal articles. PhD in Biostatistics, Epidemiology, or a related discipline.
· Experience as a collaborative biostatistician in a clinical setting.
· Ability and desire to lead an existing team of MS-level biostatisticians supporting musculoskeletal research.
· Expertise in design and analysis of complex observational studies.
· Excellent oral and written communication skills.
Interested candidates should email a curriculum vitae, the names of at least three references and a letter summarizing experience, research interests, and fit for the position to [email protected] Review of applications will begin immediately and continue until the position is filled.
Stephanie Kocian
[email protected]
The Cleveland Clinic Department of Quantitative Health Sciences has a faculty opening, at the Cleveland Ohio Main Campus, for an early to mid-career biostatistician with interest in a long-term commitment to lead biostatical collaborations with Cleveland Clinic's Lou Ruvo Center for Brain Health (LRCBH). The center is dedicated to the care of patients with memory loss, dementia and other cognitive/behavioral disorders of aging, the pursuit of a better understanding of the underlying pathobiology of these disorders, and the development of more effective treatments.
The primary need for the next five-eight years is for the statistical expert to be able to leverage multiplex analyte platforms, proteomic data and MRI/PET imaging along with clinical variables to help develop data driven disease progression models and risk assessment. The successful candidate will lead biostatistical design and analysis for observational studies and clinical trials. Additional expertise in one or more of the following areas would be desirable: novel clinical trial design, developing computational pipelines for high-dimensional data analysis, modelling multidimensional datasets, machine learning, omics analyses, longitudinal modeling, structural equations modeling, use of electronic medical record data, and adaptive network analysis.
This is a hard-money position with no explicit requirements to obtain salary support.
The position is 70% collaboration and 30% protected time for independent research.
Interested candidates should email a curriculum vitae, research statement, names of at least three references and a cover letter summarizing experience, research interests, and fit for the position to [email protected]
Review of applications will begin April 2024 and continue until the position is filled.
Stephanie Kocian
[email protected]
The Cleveland Clinic Health System (CC) is searching for a doctoral level faculty member to join its multidisciplinary Department of Quantitative Health Sciences on the Cleveland, Ohio main campus. This is a full-time position consisting of 70% designing/analyzing clinical trials and observational studies with investigators from the CC’s Digestive Disease and Surgery Institute (DDSI), and 30% independent research. A doctoral degree with expertise in biostatistics and/or epidemiology is required. The position includes a non-tenured appointment to the Cleveland Clinic Lerner College of Medicine of Case Western Reserve University at rank commensurate with experience. Candidates should enjoy collaborating on and bringing creative analytic approaches to complex problems in health care and have a strong desire to publish journal articles. Excellent English written and oral communication skills are essential. Knowledge of and experience with design and analytical methods for clinical trials. Expertise in design and analysis of complex observational studies is desirable but not required. Ability and desire to lead a team of MS-level biostatisticians supporting DDSI research.This is a ‘hard money’ position with no explicit requirements to obtain salary support. Interested candidates should email a curriculum vitae, the names of at least three references and a letter summarizing experience, research interests, and fit for the position to [email protected]. Review of applications will begin March 2023 and continue until the position is filled.
Stephanie Kocian
[email protected]
The Center for Computational Life Sciences at Cleveland Clinic offers multiple faculty positions in contemporary AI/ML and/or quantum computational sciences for promising scientists to contribute to our biomedical research and healthcare system as innovative independent thought leaders.
Research areas of particular interest include analysis of multi-modal data including real-world data/electronic health records, genomics, and machine learning (including quantum machine learning). These faculty positions (rank commensurate with experience) will shape and expand contemporary AI/ML technologies or emerging quantum computing applications centered around biomedical science and healthcare, supported by strong institutional commitment. The Center for Computational Life Sciences serves as a multi-institutional hub for collaborative research in computational life sciences and biomedicine positioned at the intersection of biology, healthcare, computer science, quantum computing, predictive modeling, simulation, AI, and disruptive computing. Cleveland Clinic’s electronic health record (EHR) is one of the largest in the world, containing more than 20 years of data on over 7 million patients. The Lerner Research Institute conducts cutting-edge basic and translational research across the four impact areas of Cancer, Brain and Vision, Inflammation and Immunity, and Heart and Vascular diseases. With continuous streams of longitudinal, multi-modal, large volume clinical and research data (in-vitro, in-vivo, and pre-clinical), computational and data sciences at Cleveland Clinic are ripe for innovation. These positions will have dedicated access to Cleveland Clinic’s data and computing infrastructure supported by a strong research partnership with IBM. The first private sector, on-premises IBM Eagle Quantum System (127 Qubit) in the United States is located on Cleveland Clinic’s main campus. In the coming years, the first of IBM’s next-generation 1,000+ qubit quantum systems will follow.
These Faculty will join the Center for Computational Life Sciences programs that span artificial intelligence, quantum computing, and digital technologies that actively engage with universities, government, industry, start-ups and other relevant organizations globally and as part of Cleveland Clinic’s role in the Cleveland Innovation District. Cleveland Clinic launched many initiatives to enrich clinic and research data including the creation of an enterprise data vault as well as a clinical research data warehouse. Cleveland Clinic continuously works to improve the quality, governance, and democratization of its data to enhance and accelerate research. The program will elevate Cleveland Clinic as the leader for a new ecosystem for computational life sciences, focused on advancing computational biomedicine through the development and application of scalable tools and techniques fit for the transdisciplinary problems in biosciences. The Faculty’s research program will be located in the newly constructed state-of-the-art research space for the Center. Rank will be commensurate with experience (Assistant Staff and above); the most competitive applicants will be those who already have an established independent research program (e.g. 2-4 years).
The Cleveland Clinic offers a very generous seed package that includes salary support. The Faculty efforts are fully focused on research; teaching opportunities may be available for interested faculty within Cleveland Clinic Lerner College of Medicine, and graduate programs in partnering institutes.
Job Requirements
Essential Duties and Responsibilities
Major duties include:
Interested candidates should email a curriculum vitae, the names of at least three references and a letter summarizing experience, research interests, current funding sources (if applicable), and current team composition to [email protected]. Review of applications will occur on a rolling basis and continue until the positions are filled.
These positions are central and critical for growth and sustainability of computational biomedicine at the Cleveland Clinic.
Description of Cleveland Clinic Infrastructure for Health care Innovation
Cleveland Clinic has operated for over 100 years on the principle of bringing innovative teams together to provide better care for patients worldwide. Today, Cleveland Clinic is a world leader in science-based healthcare (see: Cleveland Clinic Main Campus Tour video). Our strategic plan for Research Development will harness information technology to power significant advances in both personalized and population medicine. A major component of the strategy will be our anchor role in building the Cleveland Innovation District. This unprecedented collaboration includes participation and investment by the State of Ohio along with 5 independent Cleveland healthcare and academic institutions and is designed to transform research, education, and economic opportunities in Northeast Ohio and globally.
As part of the Cleveland Innovation District, Cleveland Clinic has pledged to double its research footprint and output in the next five years and create thousands of new jobs. A substantial part of this commitment involves the creation of the Global Center for Pathogen & Human Health Research. A major goal of the center is to develop the means to prevent or combat the next pandemic or global health crisis and it will operate under the tandem principles of “Discover without Limits” and “Transform Discovery into Practice.”
The Global Center resides in 400,000 square feet of newly constructed research space housing state-of-the-art laboratories and technologies. Cleveland Clinic’s international clinical care footprint provides a large, growing, and diverse patient population giving our research teams access to tens of thousands of unique biological samples through the centralized Cleveland Clinic BioRepository. Furthermore, the Discovery Accelerator, a newly established partnership with IBM Research, will leverage high- performance computing using hybrid cloud, artificial intelligence (AI), and quantum computing technologies to empower and accelerate big data research. The newly established Center for Therapeutic Discovery provides a full-scale drug discovery effort to identify new drug targets and therapies.
Cleveland Clinic is pleased to be an equal employment/affirmative action employer: Women/Minorities/Veterans/Individuals with Disabilities are encouraged to apply.
We are a smoke/drug free environment.
Kathleen Babb
[email protected]
Learn more about Cleveland Clinic's culture, benefits and career development opportunities on the Cleveland Clinic jobs website.
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