Innovation

Cleveland Clinic’s Department of Biomedical Engineering is committed to investigation, innovation, and translation of scientific discoveries to enhance patient care. Medical innovation is at the heart of our mission – indeed, our "calling" – and we have a proven track record of patenting and product commercialization.


Volcano and the Cleveland Clinic engaged in a development relationship for the Clinic’s coronary plaque characterization technology, which has resulted in its commercial availability in Volcano’s industry-leading intravascular ultrasound (IVUS) product line. VH® IVUS technology uses advanced, proprietary spectral analysis techniques to classify plaque into 4 tissue types with 93-97% accuracy. Based on 10 years of research with over 200 scientific publications in peer-reviewed journals, the technology allows for simplified image interpretation and a complete view into the severity of a patient's disease. For more information visit: www.vhivus.com

Cleveland Heart, Inc. has partnered with the Cleveland Clinic to develop the next generation of mechanical cardiac circulatory assist devices with the potential to provide a complete range of treatment options for patients suffering from irreversible end-stage heart failure. Cleveland Heart’s novel cardiac assist technology was invented and championed by a team in Cleveland Clinic’s department of Biomedical Engineering led by Leonard Golding MD. Products in development include a left ventricular assist device for treatment of heart failure and a total artificial heart replacement. For more information visit: www.clevelandheart.com

Search BME Patents

  • Patent Title:
    OR
  • First Named Inventor:
US Patent Patent Title Issue Date First-Named Inventor
8,138,265 Hydroxyphenyl cross-linked macromolecular network and applications thereof 03/20/2012 Anthony Calabro Ph.D.
8,137,688 Hydroxyphenyl cross-linked macromolecular network and applications thereof 03/20/2012 Anthony Calabro Ph.D.
8,068,670 Image Analysis of Biological Objects 11/29/2011 George F. Muschler M.D.
8,021,350 Hydroxyphenyl Cross-Linked Macromolecular Network and Applications Thereof 9/20/2011 Anthony Calabro Ph.D.
7,948,503 Techniques for 3-D Elastic Spatial Registration of Multiple Modes of Measuring a Body 5/24/2011 Raj Shekhar Ph.D.
7,940,969 System and Method of Characterizing Vascular Tissue 4/10/2011 D. Geoffrey Vince Ph.D.
7,935,058 Method for Measuring Biomechanical Properties in an Eye^ 5/3/2011 William Dupps M.D.
7,927,275 System and Method for Characterizing Vascular Tissue 4/19/2011 D. Geoffrey Vince Ph.D.
7,904,134 Brain Stimulation Models, Systems, Devices and Methods 3/8/2011 Jaimie Henderson M.D.
7,878,208 Method and Appratus for Determining a Charaterisitc of an In Vivo Sensor 2/1/2011 James Talman
7,874,990 System and method for determining a transfer function 1/25/2011 Anuja Nair
7,860,548 Brain Stumulation Models, Systems, Devices and Methods 12/28/2010 Jaimie Henderson M.D.
7,796,815 Image Analysis of Biological Objects 9/14/2010 George F. Muschler M.D.
7,776,083 Bioprosthetic Cardiovascular Valve System 8/17/2010 Ivan S. Vesely Ph.D.
7,771,351 Method and Apparatus for Eddy Current Compensation in a Radio Probe 8/10/2010 Aaron Fleischman Ph.D.
7,769,470 Neuromodulation Device and Method of Using Same 8/3/2010 Ali Rezai M.D.
7,728,442 Method and Apparatus for In Vivo Sensing 10/23/2007 Aaron Fleischman Ph.D.
7,704,054 Two-Stage Rotodynamic Blood Pump^ 4/27/2010 David J. Horvath
7,689,021 Segmentation of Regions in Measurements of A Body Based on a Deformable Model 3/30/2010 Raj Shekhar Ph.D.
7,680,526 System and Method For Obtaining a Volume of Influence Based on Non-Uniform Tissue Conductivity Data 3/16/2010 Jaimie Henderson M.D.
7,678,064 Apparatus for Detecting Tactile Sensitivity^ 3/16/2010 Barry Kuban
7,540,963 Ultrafiltration membrane,device, bioartificial organ, and methods 6/2/2009 Shuvo Roy Ph.D.
7,491,179 Apparatus and Methods for Assessing Loads on Adjacent Bones 2/17/2009 Aaron Fleischman Ph.D.
7,465,766 Hydroxyphenyl Cross-Linked Macromolecular Network and Applications Thereof 12/16/2008 Anthony Calabro Ph.D.
7,463,759 System and Method for Vascular Border Detection 12/9/2008 D. Geoffrey Vince Ph.D.
7,454,251 Excess Lead Retaining and Management Devices and Methods of Using Same 11/18/2008 Ali Rezai M.D.
7,368,502 Hydroxyphenyl Cross-Linked Macromolecular Network and Applictions Thereof 5/6/2008 Anthony Calabro Ph.D.
7,359,554 System and Method for Identifying a Vascular Border 4/15/2008 Jon D. Klingensmith Ph.D.
7,346,382 Brain Stimulation Models, Systems, Devices, and Methods 3/18/2008 Cameron McIntyre Ph.D
7,280,710 Architecture for Real-Time 3D Image Registration 10/9/2007 Raj Shekhar Ph.D.
7,262,068 Microneedle array module and method for fabricating same 8/28/2007 Shuvo Roy Ph.D.
7,215,802 System and Method for Identifying a Vascular Border Detection 5/8/2007 Jon D. Klingensmith Ph.D.
7,189,260 Ventricular Assist System Secondary Impeller 3/13/2007 Leonard A. Golding M.D.
7,182,736 Apparatus and method for assessing loads on adjacent bones 2/27/2007 Aaron Fleischman Ph.D.
7,181,288 Neuromodulation Device and Method of Using Same (Volumetric Electrode) 2/20/2007 Ali Rezai M.D.
7,169,106 Intraocular Pressure Measurement System Including a Sensor Mounted in a Contact Lens 1/30/2007 Aaron Fleischman Ph.D.
7,074,188 System and Method for Characterizing Vascular Tissue 7/11/2006 Anuja Nair
7,048,856 Ultrafiltration Membrane, Device, Bioartificial Organ, and Methods ^ 5/23/2006 Shuvo Roy Ph.D.
7,011,681 Bioprosthetic Cardiovascular Valve System 3/14/2006 Ivan S. Vesely Ph.D.
6,994,672 Apparatus and method for measuring intraocular pressure 2/7/2006 Aaron Fleischman Ph.D.
6,982,298 Hydroxyphenyl Cross-Linked Macromolecular Network and Applictions Thereof 1/3/2006 Anthony Calabro Ph.D.
6,802,806 Apparatus for use with an inflow cannula of ventricular assist device 10/12/2004 Patrick M. McCarthy M.D.
6,790,372 Microneedle array module and method for fabricating same 9/14/2004 Shuvo Roy Ph.D.
6,749,568 Intraocular pressure measurement system including a sensor mounted in a contact lens 6/15/2004 Aaron Fleischman Ph.D.
6,706,005 Apparatus and method for assessing loads on adjacent bones 3/16/2004 Shuvo Roy Ph.D.
6,682,490 Apparatus and method for monitoring a condition inside the body cavity 1/27/2004 Shuvo Roy Ph.D.
6,641,540 Miniature ultrasonic transducer 11/4/2003 Aaron Fleischman Ph.D.
6,623,984 MEMS-Based Integrated Magnetic Particle Identification System 9/23/2003 Jeff Chalmers Ph.D.
6,569,196 System for Minimally Invasive Insertion of a Bioprosthetic Heart Valve 5/27/2003 Ivan S. Vesely Ph.D.
6,557,430 SYSTEM AND DEVICE FOR DETERMINING PARTICLE CHARACTERISTICS 5/6/2003 Maciej Zborowski Ph.D
6,534,004 Processing of implantable animal tissues for dry storage 3/18/2003 Ji-Feng Chen
6,468,285 Surgical Instruments and Procedures 10/22/2002 Thomas Hsu M.D.
6,467,630 Continuous Particle and Molecule Separation with an Annular Flow Channel 10/22/2002 Jeff Chalmers Ph.D.
6,447,449 System for measuring intraocular pressure of an eye and a mem sensor for use therewith 9/10/2002 Aaron Fleischman Ph.D.
6,412,359 System and Device for Determining Particle Characteristics 7/2/2002 Maciej Zborowski Ph.D
6,391,610 Nucleic Acids Encoding Zinc Metalloproteases 5/21/2002 Suneel S. Apte D.Phil
6,381,350 Intravascular Ultrasonic Analysis Using Active Contour Method and System 4/30/2002 Jon D. Klingensmith Ph.D.
6,366,797 Method and system for brain volume analysis 4/2/2002 Elizabeth Fisher
6,200,268 Vascular plaque characterization 3/13/2001 D. Geoffrey Vince Ph.D.
6,186,999 Rigid clampable cannula 2/13/2001 Ji-Feng Chen
6,142,025 Method for Determing Particle Characteristics 11/7/2000 Maciej Zborowski Ph.D
6,120,735 Fractional cell sorter 9/19/2000 Maciej Zborowski Ph.D
6,082,205 System and device for determining particle characteristics 7/4/2000 Maciej Zborowski Ph.D
5,974,901 System and Device for Determining Particle Characteristics 11/2/1999 Maciej Zborowski Ph.D
5,968,820 Fractional cell sorter 10/19/1999 Maciej Zborowski Ph.D
5,890,883 Rotodynamic pump with non-circular hydrodynamic bearing journal 4/6/1999 Leonard A. Golding M.D.
5,871,692 Method and apparatus for cleaning, decontaminating, and sterilizing catheters 2/16/1999 Donna M. Haire
5,626,579 Bone transport and lengthening system 5/6/1997 George F. Muschler M.D.
5,429,638 Bone transport and lengthening system 7/4/1995 George F. Muschler M.D.
5,370,509 Sealless rotodynamic pump with fluid bearing 12/6/1994 Leonard A. Golding M.D.
5,324,177 Sealless rotodynamic pump with radially offset rotor 6/28/1994 Leonard A. Golding M.D.
5,145,333 Fluid motor driven blood pump 9/8/1992 Leonard A. Golding M.D.
5,118,264 Purge flow control in rotary blood pumps 6/2/1992 William A. Smith D.Phil
5,098,256 Viscous seal blood pump 3/24/1992 William A. Smith D.Phil
5,006,104 Heart pump having contractible guide mechanism for pusher plate 4/9/1991 William A. Smith D.Phil